2-Mercaptobenzimidazole

An aromatic thiol, C7H6N2S, 150.206 g/mol. Melting point 577 to 579 °F, density 1.42 (NTP, 1992) - Denser than water; will sink, as published.

verified recordOrganic — aromatic thiol5 measured properties

Identifiers

Molecular formula: C₇H₆N₂S
Molecular weight: 150.206 g/mol
Exact mass: 150.025169 g/mol
IUPAC name: 1H-benzimidazole-2-thiol
SMILES: Sc1nc2ccccc2[nH]1
InChI: InChI=1S/C7H6N2S/c10-7-8-5-3-1-2-4-6(5)9-7/h1-4H,(H2,8,9,10)
InChIKey: YHMYGUUIMTVXNW-UHFFFAOYSA-N

Open in ReactionLens Use in reaction prediction

Measured properties

Published measurements, each with its source. Two readings of one property are both shown, in the units each used.

Melting Point: 577 to 579 °F (NTP, 1992)measured · National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
Solubility: less than 1 mg/mL at 74.3 °F (NTP, 1992)measured · National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.; >22.5 [ug/mL] (The mean of the results at pH 7.4)measured · reference compound database
Density: 1.42 (NTP, 1992) - Denser than water; will sinkmeasured · National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
Vapor Pressure: 30.2 mmHg at 142 °F (NTP, 1992)measured · National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.; 0.00000466 [mmHg]measured · reference compound database
LogP: 1.66measured · reference compound database

Calculated properties

Derived from the structure, not from a sample; kept apart from the measurements above.

Molecular weight: 150.2 g/molcalculated · reference compound database; Average mass of one molecule, from reference compound database.
Exact mass: 150.02516937 Dacalculated · reference compound database; Mass of the most common isotopic form.
XLogP3: 1.7calculated · reference compound database; Estimated oil/water partition, computed by reference compound database.
Polar surface area: 29.7 Å²calculated · reference compound database; Polar surface area as computed by reference compound database.
Complexity: 129calculated · reference compound database; A rough measure of how intricate the structure is.
H-bond donors: 2calculated · reference compound database
H-bond acceptors: 2calculated · reference compound database
logP: 1.8516calculated · chemistry engine; Estimated preference for oil over water. Higher means more oil-like.
Topological polar surface area: 28.68 Å²calculated · chemistry engine; Surface area from polar atoms; relates to how easily a molecule crosses membranes.
H-bond donors: 2calculated · chemistry engine; Atoms that can donate a hydrogen bond.
H-bond acceptors: 2calculated · chemistry engine; Atoms that can accept a hydrogen bond.
Rotatable bonds: 0calculated · chemistry engine; Single bonds the molecule can freely twist around.
Molar refractivity: 43.3457 cm³/molcalculated · chemistry engine; Relates to the molecule's polarisability.
Fraction sp³ carbons: 0calculated · chemistry engine; Share of carbon atoms with tetrahedral bonding.
QED drug-likeness: 0.5512calculated · chemistry engine; Quantitative estimate of drug-likeness (0–1).

What it is made of

Elements

C Carbon7 atoms · 56.0% by mass
S Sulfur1 atom · 21.3% by mass
N Nitrogen2 atoms · 18.7% by mass
H Hydrogen6 atoms · 4.0% by mass

Percentages are of the molecular weight above, worked out the same way the molar mass calculator does it.

Structure

Heavy atoms, hydrogen excluded: 10
Total atoms, hydrogen included: 16
Rings: 2
Aromatic rings: 2
Stereocentres: 0
Formal charge: 0

Functional groups

Thiol
An –SH group, the sulfur analogue of an alcohol.
Aromatic ring
A flat six-membered ring with delocalised electrons.
Aromatic ring (five-membered)
A flat five-membered ring with delocalised electrons, such as furan, thiophene or pyrrole.

Matched by structural pattern, not by a measurement.

The molecule in three dimensions

Rotate and inspect the atoms. Loaded only when you ask, so the page stays light.

The drawing above is a diagram of what is bonded to what. A molecule is not flat, and the model here is one low-energy shape generated from the connectivity — useful for seeing which groups can reach each other, and not a measured structure. A real sample is a population of conformations, interconverting.

Reactions it appears in

No documented reaction with a written procedure and a source involves 2-Mercaptobenzimidazole yet.

Other names for it

The systematic name on this record is 1H-benzimidazole-2-thiol.

The sources also call it 2-Benzimidazolethiol, 1H-Benzimidazole-2-thiol, Antioxidant MB, o-Phenylenethiourea, Antigene MB, Antigen MB, Permanax 21, AOMB, Antiegene MB, 2-MERCAPTOBENZOIMIDAZOLE, 2H-Benzimidazole-2-thione, 1,3-dihydro-, 2-Thiobenzimidazole.

Structurally related

Nothing structurally close to 2-Mercaptobenzimidazole has a page here yet.

Seen alongside it in reaction records

Molecules that appear in the same recorded reactions as 2-Mercaptobenzimidazole. This says nothing about structure: most of them are the bases, solvents, ligands and catalysts the chemistry needed, and they are here because somebody put them in the same flask.

1,4-Dimethyl-8-(2-benzimidazolyl)thiomethyl-1,2-dihydroquinoline

formed as a product

C₁₉H₁₉N₃S, 321.449 g/mol.

(1,3)Oxazolo(4,5-b)pyridine-2-thiol

used as a reactant

C₆H₄N₂OS, 152.178 g/mol.

1,4-Dimethyl-8-chloromethyl-1,2-dihydroquinoline

used as a reactant

C₁₂H₁₄ClN, 207.704 g/mol.

Where these values came from

reference compound database11410
compound record
chemistry engine
structure perception

compound record.

What this page does not claim

Identifiers are copied from the source record, measured values are reported as published, and calculated values are marked as calculated. Nothing here is a hazard, purity or handling assessment — how the library is checked.