Ethylenediaminetetraacetic Acid

A carboxylic acid, C10H16N2O8, 292.244 g/mol. Melting point 237 °C, density Relative density (water = 1): 0.86, as published.

verified recordOrganic — carboxylic acid6 measured properties

Identifiers

Molecular formula: C₁₀H₁₆N₂O₈
Molecular weight: 292.244 g/mol
Exact mass: 292.090665 g/mol
IUPAC name: 2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid
SMILES: O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O
InChI: InChI=1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)
InChIKey: KCXVZYZYPLLWCC-UHFFFAOYSA-N

Open in ReactionLens Use in reaction prediction

Measured properties

Published measurements, each with its source. Two readings of one property are both shown, in the units each used.

Melting Point: 237 °Cmeasured · DrugBank; 245 °Cmeasured · Hazardous Substances Data Bank (HSDB)
Density: 0.86 at 68 °F (USCG, 1999) - Less dense than water; will floatmeasured · CAMEO Chemicals; Relative density (water = 1): 0.86measured · ILO-WHO International Chemical Safety Cards (ICSCs)
Solubility: 1000000 mg/L at 25 °Cmeasured · DrugBank; SOL IN SOLN OF ALKALI HYDROXIDESmeasured · Hazardous Substances Data Bank (HSDB)
Vapor Pressure: 1.50X10-12 mm Hg at 25 °C /Extrapolated/measured · Hazardous Substances Data Bank (HSDB)
LogP: -2.6measured · DrugBank; -2.6measured · Human Metabolome Database (HMDB)
Flash Point: Flash point is> 100 °C,measured · Hazardous Substances Data Bank (HSDB)

Calculated properties

Derived from the structure, not from a sample; kept apart from the measurements above.

Molecular weight: 292.24 g/molcalculated · reference compound database; Average mass of one molecule, from reference compound database.
Exact mass: 292.09066547 Dacalculated · reference compound database; Mass of the most common isotopic form.
XLogP3: -5.9calculated · reference compound database; Estimated oil/water partition, computed by reference compound database.
Polar surface area: 156 Å²calculated · reference compound database; Polar surface area as computed by reference compound database.
Complexity: 315calculated · reference compound database; A rough measure of how intricate the structure is.
H-bond donors: 4calculated · reference compound database
H-bond acceptors: 10calculated · reference compound database
logP: -2.0712calculated · chemistry engine; Estimated preference for oil over water. Higher means more oil-like.
Topological polar surface area: 155.68 Å²calculated · chemistry engine; Surface area from polar atoms; relates to how easily a molecule crosses membranes.
H-bond donors: 4calculated · chemistry engine; Atoms that can donate a hydrogen bond.
H-bond acceptors: 6calculated · chemistry engine; Atoms that can accept a hydrogen bond.
Rotatable bonds: 11calculated · chemistry engine; Single bonds the molecule can freely twist around.
Molar refractivity: 63.4232 cm³/molcalculated · chemistry engine; Relates to the molecule's polarisability.
Fraction sp³ carbons: 0.6calculated · chemistry engine; Share of carbon atoms with tetrahedral bonding.
QED drug-likeness: 0.3333calculated · chemistry engine; Quantitative estimate of drug-likeness (0–1).

What it is made of

Elements

O Oxygen8 atoms · 43.8% by mass
C Carbon10 atoms · 41.1% by mass
N Nitrogen2 atoms · 9.6% by mass
H Hydrogen16 atoms · 5.5% by mass

Percentages are of the molecular weight above, worked out the same way the molar mass calculator does it.

Structure

Heavy atoms, hydrogen excluded: 20
Total atoms, hydrogen included: 36
Rings: 0
Aromatic rings: 0
Stereocentres: 0
Formal charge: 0

Functional groups

Carboxylic acid
A carbon double-bonded to oxygen and bonded to an –OH group; acidic.
Tertiary amine
Nitrogen bonded to three carbons.

Matched by structural pattern, not by a measurement.

The molecule in three dimensions

Rotate and inspect the atoms. Loaded only when you ask, so the page stays light.

The drawing above is a diagram of what is bonded to what. A molecule is not flat, and the model here is one low-energy shape generated from the connectivity — useful for seeing which groups can reach each other, and not a measured structure. A real sample is a population of conformations, interconverting.

Reactions it appears in

No documented reaction with a written procedure and a source involves Ethylenediaminetetraacetic Acid yet.

Other names for it

The systematic name on this record is 2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid.

The sources also call it EDTA, Edetic acid, Edathamil, Sequestrol, Havidote, Titriplex, Cheelox, EDTA acid, Sequestrene aa, Versene acid, Trilon BS.

Structurally related

Nothing structurally close to Ethylenediaminetetraacetic Acid has a page here yet.

Seen alongside it in reaction records

Molecules that appear in the same recorded reactions as Ethylenediaminetetraacetic Acid. This says nothing about structure: most of them are the bases, solvents, ligands and catalysts the chemistry needed, and they are here because somebody put them in the same flask.

(S)-methyl 2-((tert-butoxycarbonyl)amino)-3-(1H-imidazol-4-yl)propanoate

used as a reactant

C₁₂H₁₉N₃O₄, 269.301 g/mol.

1,4-Dioxane

used as a reactant

C₄H₈O₂, 88.106 g/mol.

Where these values came from

reference compound database6049
compound record
chemistry engine
structure perception

compound record.

What this page does not claim

Identifiers are copied from the source record, measured values are reported as published, and calculated values are marked as calculated. Nothing here is a hazard, purity or handling assessment — how the library is checked.