Sulfanilic acid

An aromatic amine, C6H7NO3S, 173.193 g/mol. Melting point 288 °C decomposes without melting, density 1.485 at 25 °C/4 °C, as published.

verified recordOrganic — aromatic amine5 measured properties

Identifiers

Molecular formula: C₆H₇NO₃S
Molecular weight: 173.193 g/mol
Exact mass: 173.014664 g/mol
IUPAC name: 4-aminobenzenesulfonic acid
SMILES: Nc1ccc(S(=O)(=O)O)cc1
InChI: InChI=1S/C6H7NO3S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H,8,9,10)
InChIKey: HVBSAKJJOYLTQU-UHFFFAOYSA-N

Open in ReactionLens Use in reaction prediction

Measured properties

Published measurements, each with its source. Two readings of one property are both shown, in the units each used.

Melting Point: Decomposes without melting at 550 °F (NTP, 1992)measured · CAMEO Chemicals; 288 °C decomposes without meltingmeasured · Hazardous Substances Data Bank (HSDB)
Density: 1.485 at 77 °F (NTP, 1992) - Denser than water; will sinkmeasured · CAMEO Chemicals; 1.485 at 25 °C/4 °Cmeasured · Hazardous Substances Data Bank (HSDB)
Solubility: less than 1 mg/mL at 68 °F (NTP, 1992)measured · CAMEO Chemicals; Insoluble in ethanol and ethermeasured · Hazardous Substances Data Bank (HSDB)
Vapor Pressure: 0.0000002 [mmHg]measured · Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
LogP: log Kow = -2.16measured · Hazardous Substances Data Bank (HSDB); -0.9measured · ILO-WHO International Chemical Safety Cards (ICSCs)

Calculated properties

Derived from the structure, not from a sample; kept apart from the measurements above.

Molecular weight: 173.19 g/molcalculated · reference compound database; Average mass of one molecule, from reference compound database.
Exact mass: 173.01466426 Dacalculated · reference compound database; Mass of the most common isotopic form.
XLogP3: -0.6calculated · reference compound database; Estimated oil/water partition, computed by reference compound database.
Polar surface area: 88.8 Å²calculated · reference compound database; Polar surface area as computed by reference compound database.
Complexity: 210calculated · reference compound database; A rough measure of how intricate the structure is.
H-bond donors: 2calculated · reference compound database
H-bond acceptors: 4calculated · reference compound database
logP: 0.5155calculated · chemistry engine; Estimated preference for oil over water. Higher means more oil-like.
Topological polar surface area: 80.39 Å²calculated · chemistry engine; Surface area from polar atoms; relates to how easily a molecule crosses membranes.
H-bond donors: 2calculated · chemistry engine; Atoms that can donate a hydrogen bond.
H-bond acceptors: 3calculated · chemistry engine; Atoms that can accept a hydrogen bond.
Rotatable bonds: 1calculated · chemistry engine; Single bonds the molecule can freely twist around.
Molar refractivity: 40.669 cm³/molcalculated · chemistry engine; Relates to the molecule's polarisability.
Fraction sp³ carbons: 0calculated · chemistry engine; Share of carbon atoms with tetrahedral bonding.
QED drug-likeness: 0.4788calculated · chemistry engine; Quantitative estimate of drug-likeness (0–1).

What it is made of

Elements

C Carbon6 atoms · 41.6% by mass
O Oxygen3 atoms · 27.7% by mass
S Sulfur1 atom · 18.5% by mass
N Nitrogen1 atom · 8.1% by mass
H Hydrogen7 atoms · 4.1% by mass

Percentages are of the molecular weight above, worked out the same way the molar mass calculator does it.

Structure

Heavy atoms, hydrogen excluded: 11
Total atoms, hydrogen included: 18
Rings: 1
Aromatic rings: 1
Stereocentres: 0
Formal charge: 0

Functional groups

Primary aromatic amine
An –NH2 group attached directly to an aromatic ring, as in aniline. Much less basic than an alkyl amine, because the lone pair is delocalised into the ring.
Sulfonic acid
A sulfur bonded to three oxygens including an –OH.
Aromatic ring
A flat six-membered ring with delocalised electrons.

Matched by structural pattern, not by a measurement.

The molecule in three dimensions

Rotate and inspect the atoms. Loaded only when you ask, so the page stays light.

The drawing above is a diagram of what is bonded to what. A molecule is not flat, and the model here is one low-energy shape generated from the connectivity — useful for seeing which groups can reach each other, and not a measured structure. A real sample is a population of conformations, interconverting.

Reactions it appears in

No documented reaction with a written procedure and a source involves Sulfanilic acid yet.

Other names for it

The systematic name on this record is 4-aminobenzenesulfonic acid.

The sources also call it 4-Aminobenzenesulfonic acid, Sulphanilic acid, p-Aminobenzenesulfonic acid, Aniline-4-sulfonic acid, Aniline-p-sulfonic acid, Sulfanilsaeure, Aniline-p-sulphonic acid, p-Aminophenylsulfonic acid, p-Anilinesulfonic acid, Kyselina sulfanilova, p-sulfoaniline.

Structurally related

Nothing structurally close to Sulfanilic acid has a page here yet.

Where these values came from

reference compound database8479
compound record
chemistry engine
structure perception

compound record.

What this page does not claim

Identifiers are copied from the source record, measured values are reported as published, and calculated values are marked as calculated. Nothing here is a hazard, purity or handling assessment — how the library is checked.