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Urea

CH4N2O, 60.056 g/mol. Its structure, the values that were measured, the values that were calculated, and where each one came from.

Inorganic compound7 measured properties

Drawn from the SMILES. It shows how the atoms are connected — not a photograph of a molecule, and not its shape in space.

Identifiers

Molecular formula
CH₄N₂O
Molecular weight
60.056 g/mol
Exact mass
60.032363 g/mol
SMILES
NC(N)=O
InChI
InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
InChIKey
XSQUKJJJFZCRTK-UHFFFAOYSA-N

Both are open without an account.

Measured properties

Values somebody obtained from a sample and published. Where two sources report the same property they are both shown, in the units each used — a disagreement between them is information, and averaging it away would be inventing a number neither one gave.

Boiling Point
Decomposes (NTP, 1992)measured · National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
Decomposesmeasured · Verschueren, K. Handbook of Environmental Data on Organic Chemicals. 3rd ed. New York, NY: Van Nostrand Reinhold Co., 1996., p. 1876
Melting Point
275 °F (NTP, 1992)measured · National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
132.7 °Cmeasured · PhysProp
132 °C to 135 °Cmeasured · reference compound database
132.70 °Cmeasured · Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 13th ed. New York, NY: John Wiley & Sons, Inc. 1997., p. 1157
Ionization potential = 9 eV; Latent heat of fusion = 15.4 kJ/mol (at melting point); Latent heat of sublimation = 87.9 kJ/mol @ 25 °C; Heat of formation = -333.7 kJ/mol @ 25 °C; Decomposition temp = 135 °Cmeasured · Environment Canada; Tech Info from Problem Spills: Urea p. 4 (1985)
132 °Cmeasured · reference compound database
132.7-135 °Cmeasured · reference compound database
132.7 °Cmeasured · reference compound database
Solubility
Soluble (NTP, 1992)measured · National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
545000 mg/L (at 25 °C)measured · YALKOWSKY,SH (1989)
Very soluble in water; Soluble in ethanolmeasured · reference compound database
10 ml 95% alc, 6 ml methanol, 1 ml boiling 95% alc, 20 ml abs alc, 2 ml glycerol; almost insol in chloroform, ether; sol in concn HClmeasured · Budavari, S. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 1996., p. 1683
INSOL IN BENZENE; SOL IN ACETIC ACIDmeasured · Weast, R.C. (ed.). Handbook of Chemistry and Physics. 60th ed. Boca Raton, Florida: CRC Press Inc., 1979., p. C-536
Sol in pyrimidinemeasured · Lide, D.R. (ed). CRC Handbook of Chemistry and Physics. 72nd ed. Boca Raton, FL: CRC Press, 1991-1992., p. 3-509
In water, 5.45X10+5 mg/l @ 25 °Cmeasured · Yalkowsky SH; Arizona Database of Aqueous Solubilities. Univ of AZ, College of Pharmacy (1989)
545.0 mg/mLmeasured · reference compound database
Solubility in water: misciblemeasured · reference compound database
>9 [ug/mL] (The mean of the results at pH 7.4)measured · reference compound database
Density
1.34 at 68 °F (USCG, 1999) - Denser than water; will sinkmeasured · U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
1.3230 @ 20 °C/4 °Cmeasured · Lide, DR (ed.). CRC Handbook of Chemistry and Physics. 81st Edition. CRC Press LLC, Boca Raton: FL 2000, p. 3-328
On further heating it decomp to biuret, NH3, cyanuric acid; pH of 10% water soln: 7.2; density of water soln (wt/wt): 1.027 @ 10%; 1.054 @ 20%; 1.145 @ 50%measured · Budavari, S. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 1996., p. 1683
g/cm³measured · reference compound database
1.335 @25 °Cmeasured · reference compound database
Vapor Pressure
0.000012 [mmHg]measured · reference compound database
1.2X10-5 mm Hg @ 25 °Cmeasured · Jones AH; J Chem Eng Data 5: 196-200 (1960)
LogP
-2.11measured · HANSCH,C ET AL. (1995)
log Kow = -2.11measured · Hansch, C., Leo, A., D. Hoekman. Exploring QSAR - Hydrophobic, Electronic, and Steric Constants. Washington, DC: American Chemical Society., 1995., p. 3
-2.11measured · HANSCH,C ET AL. (1995)
-3.00/-1.54measured · reference compound database
-1.54measured · reference compound database
Viscosity
1.78 mPa-s (46% solution @ 20 °C); 1.81 mP-s @ 137 °C; 1.90 mPa-s (saturated solution @ 20 °C)measured · Environment Canada; Tech Info from Problem Spills: Urea p. 4 (1985)

Calculated properties

Derived from the structure rather than from a sample. These are reproducible and they are not measurements: a calculated partition coefficient and a measured one can differ by a long way, and where both exist they are listed apart on purpose.

logP
-0.9762calculated · chemistry engine
Estimated preference for oil over water. Higher means more oil-like.
Topological polar surface area
69.11 Ųcalculated · chemistry engine
Surface area from polar atoms; relates to how easily a molecule crosses membranes.
H-bond donors
2calculated · chemistry engine
Atoms that can donate a hydrogen bond.
H-bond acceptors
1calculated · chemistry engine
Atoms that can accept a hydrogen bond.
Rotatable bonds
0calculated · chemistry engine
Single bonds the molecule can freely twist around.
Molar refractivity
13.7708 cm³/molcalculated · chemistry engine
Relates to the molecule's polarisability.
Fraction sp³ carbons
0calculated · chemistry engine
Share of carbon atoms with tetrahedral bonding.
QED drug-likeness
0.3705calculated · chemistry engine
Quantitative estimate of drug-likeness (0–1).

What it is made of

Elements

Percentages are of the molecular weight above, worked out the same way the molar mass calculator does it.

Structure

Heavy atoms, hydrogen excluded
4
Total atoms, hydrogen included
8
Rings
0
Aromatic rings
0
Stereocentres
0
Formal charge
0

Functional groups

  • Amide

    A carbonyl bonded directly to nitrogen.

Matched by structural pattern, not by a measurement.

The molecule in three dimensions

Rotate and inspect the atoms. Loaded only when you ask, so the page stays light.

The drawing above is a diagram of what is bonded to what. A molecule is not flat, and the model here is one low-energy shape generated from the connectivity — useful for seeing which groups can reach each other, and not a measured structure. A real sample is a population of conformations, interconverting.

Reactions it appears in

No documented reaction with a written procedure and a source involves Urea yet.

Other names for it

No systematic name is recorded.

The sources also call it carbamide, Carbonyldiamide, Ureophil, Carbonyldiamine, Ureaphil, Keratinamin, Urevert, Alphadrate, Aquadrate, Carbaderm, Pastaron, Urepearl.

Structurally related

Nothing structurally close to Urea has a page here yet.

Seen alongside it in reaction records

Molecules that appear in the same recorded reactions as Urea. This says nothing about structure: most of them are the bases, solvents, ligands and catalysts the chemistry needed, and they are here because somebody put them in the same flask.

Where these values came from

  • chemistry engine

    structure perception

No matching record was found in the currently indexed sources (reference compound database)..

What this page does not claim

The identifiers are what the source record holds, copied rather than recomputed. Measured values are reported as their source gave them, units and all; calculated values are marked as calculated and are not measurements. Where a field is absent the page says so, because a blank cell reads as a zero and a guessed value reads as a fact.

Nothing here is a hazard assessment, a purity statement or advice about handling a sample. A flash point quoted from a safety database is a number somebody published, not a judgement by us about whether this molecule is safe for what you intend.