Dimethylacetamide
An amide, C4H9NO, 87.122 g/mol. Boiling point 329 to 331 °F at 760 mmHg, melting point -4 °F, as published. Appears in 65 documented reactions.
Identifiers
- Molecular formula
- C₄H₉NO
- Molecular weight
- 87.122 g/mol
- Exact mass
- 87.068414 g/mol
- IUPAC name
- N,N-dimethylacetamide
- CC(=O)N(C)C
- InChI=1S/C4H9NO/c1-4(6)5(2)3/h1-3H3
- FXHOOIRPVKKKFG-UHFFFAOYSA-N
Measured properties
- Boiling Point
- 329 to 331 °F at 760 mmHg (NTP, 1992)
- 331 °F at 760 mmHg (USCG, 1999)
- Melting Point
- -4 °F (NTP, 1992)
- -4 °F (USCG, 1999)
- Density
- 0.943 at 68 °F (USCG, 1999) - Less dense than water; will float
- 0.937 (USCG, 1999) - Less dense than water; will float
- Solubility
- greater than or equal to 100 mg/mL at 72 °F (NTP, 1992)
- SOL IN BENZENE
- Vapor Pressure
- 9 mmHg at 140 °F (NTP, 1992)
- 2.0 [mmHg]
- LogP
- log Kow= -0.77
- -0.77
- Flash Point
- 151 °F (NTP, 1992)
- 145 °F (USCG, 1999)
- Viscosity
- 0.92 cP @ 25 °C
- Refractive Index
- Index of refraction: 1.4230 @ 20 °C/D; 1.4358 @ 25 °C/D
Calculated properties
- Molecular weight
- 87.12 g/mol
- Exact mass
- 87.068413911 Da
- XLogP3
- -0.8
- Polar surface area
- 20.3 Ų
- Complexity
- 58
- H-bond donors
- 0
- H-bond acceptors
- 1
- logP
- 0.0945
- Topological polar surface area
- 20.31 Ų
- H-bond donors
- 0
- H-bond acceptors
- 1
- Rotatable bonds
- 0
- Molar refractivity
- 24.368 cm³/mol
- Fraction sp³ carbons
- 0.75
- QED drug-likeness
- 0.4099
What it is made of
Structure
- Heavy atoms, hydrogen excluded
- 6
- Total atoms, hydrogen included
- 15
- Rings
- 0
- Aromatic rings
- 0
- Stereocentres
- 0
- Formal charge
- 0
Functional groups
Amide
The molecule in three dimensions
The drawing above is a diagram of what is bonded to what. A molecule is not flat, and the model here is one low-energy shape generated from the connectivity — useful for seeing which groups can reach each other, and not a measured structure. A real sample is a population of conformations, interconverting.
Reactions it appears in
65 documented reactions involve Dimethylacetamide, each with a written procedure and a source, and all of them are buchwald–hartwig amination. A few are shown.
Buchwald–Hartwig amination
Buchwald–Hartwig amination · as a solvent
A recorded experiment with its conditions, its yield where one was published, and a link to the source.
Buchwald–Hartwig amination
Buchwald–Hartwig amination · as a solvent
A recorded experiment with its conditions, its yield where one was published, and a link to the source.
Buchwald–Hartwig amination
Buchwald–Hartwig amination · as a solvent
A recorded experiment with its conditions, its yield where one was published, and a link to the source.
Other names for it
The systematic name on this record is N,N-dimethylacetamide.
The sources also call it N,N-DIMETHYLACETAMIDE, Acetamide, N,N-dimethyl-, Acetdimethylamide, DMAc, Dimethyl acetamide, N,N-Dimethyl acetamide, Dimethylamide acetate, N,N-Dimethylethanamide, Dimethylacetone amide, Acetic acid, dimethylamide, Acetyldimethylamine.
Structurally related
Seen alongside it in reaction records
Molecules that appear in the same recorded reactions as Dimethylacetamide. This says nothing about structure: most of them are the bases, solvents, ligands and catalysts the chemistry needed, and they are here because somebody put them in the same flask.
Where these values came from
chemistry engine
What this page does not claim
Identifiers are copied from the source record, measured values are reported as published, and calculated values are marked as calculated. Nothing here is a hazard, purity or handling assessment — how the library is checked.
Where to next
More molecules under D
The rest of this shelf, a hundred names at a time.
Molar mass calculator
Work with C4H9NO in a calculation, with every element's contribution shown.
Molarity calculator
Grams of Dimethylacetamide for a volume and a concentration, or the concentration a mass gives.
Open in ReactionLens
The full record in the workstation: every atom, every bond, and the reactions it appears in.