Dimethylformamide
An amide, C3H7NO, 73.095 g/mol. Boiling point 153 °C, melting point -60.4 °C, as published. Appears in 27 documented reactions across 2 classes.
Identifiers
- Molecular formula
- C₃H₇NO
- Molecular weight
- 73.095 g/mol
- Exact mass
- 73.052764 g/mol
- IUPAC name
- N,N-dimethylformamide
- CN(C)C=O
- InChI=1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N
Measured properties
- Boiling Point
- 300 to 313 °F at 760 mmHg (NTP, 1992)
- 153 °C
- Melting Point
- -78 °F (NTP, 1992)
- -60.4 °C
- Density
- 0.95 at 68 °F (USCG, 1999) - Less dense than water; will float
- 0.9445 at 25 °C/4 °C
- Solubility
- greater than or equal to 100 mg/mL at 72 °F (NTP, 1992)
- 1000000 mg/L (at 25 °C)
- Vapor Pressure
- 3.7 mmHg at 77 °F ; 2.7 mmHg at 68 °F (NTP, 1992)
- 3.87 [mmHg]
- LogP
- -1.01
- log Kow = -1.01
- Flash Point
- 153 °F (NTP, 1992)
- 58 °C, closed cup
Calculated properties
- Molecular weight
- 73.09 g/mol
- Exact mass
- 73.052763847 Da
- XLogP3
- -1
- Polar surface area
- 20.3 Ų
- Complexity
- 33
- H-bond donors
- 0
- H-bond acceptors
- 1
- logP
- -0.2956
- Topological polar surface area
- 20.31 Ų
- H-bond donors
- 0
- H-bond acceptors
- 1
- Rotatable bonds
- 1
- Molar refractivity
- 19.751 cm³/mol
- Fraction sp³ carbons
- 0.6667
- QED drug-likeness
- 0.3903
What it is made of
Structure
- Heavy atoms, hydrogen excluded
- 5
- Total atoms, hydrogen included
- 12
- Rings
- 0
- Aromatic rings
- 0
- Stereocentres
- 0
- Formal charge
- 0
Functional groups
Amide
The molecule in three dimensions
The drawing above is a diagram of what is bonded to what. A molecule is not flat, and the model here is one low-energy shape generated from the connectivity — useful for seeing which groups can reach each other, and not a measured structure. A real sample is a population of conformations, interconverting.
Reactions it appears in
27 documented reactions involve Dimethylformamide, each with a written procedure and a source across 2 classes. A few from each are shown.
Decarboxylative cross-coupling
Decarboxylative cross-coupling · as a solvent
A recorded experiment with its conditions, its yield where one was published, and a link to the source.
Buchwald–Hartwig amination
Buchwald–Hartwig amination · as a solvent
A recorded experiment with its conditions, its yield where one was published, and a link to the source.
Decarboxylative cross-coupling
Decarboxylative cross-coupling · as a solvent
A recorded experiment with its conditions, its yield where one was published, and a link to the source.
Buchwald–Hartwig amination
Buchwald–Hartwig amination · as a solvent
A recorded experiment with its conditions, its yield where one was published, and a link to the source.
Decarboxylative cross-coupling
Decarboxylative cross-coupling · as a solvent
A recorded experiment with its conditions, its yield where one was published, and a link to the source.
Buchwald–Hartwig amination
Buchwald–Hartwig amination · as a solvent
A recorded experiment with its conditions, its yield where one was published, and a link to the source.
All 19 decarboxylative cross-coupling recordsAll 8 buchwald–hartwig amination records
Other names for it
The systematic name on this record is N,N-dimethylformamide.
The sources also call it N,N-DIMETHYLFORMAMIDE, Dimethyl formamide, N-Formyldimethylamine, Formamide, N,N-dimethyl-, Dimethylformamid, DMFA, N,N-Dimethyl formamide, Formyldimethylamine, Dimetilformamide, Dwumetyloformamid, Dimetylformamidu.
Structurally related
Seen alongside it in reaction records
Molecules that appear in the same recorded reactions as Dimethylformamide. This says nothing about structure: most of them are the bases, solvents, ligands and catalysts the chemistry needed, and they are here because somebody put them in the same flask.
1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride
C₈H₁₈ClN₃, 191.706 g/mol.
1,3,5-Triethylbenzene
C₁₂H₁₈, 162.276 g/mol.
1,3-Diethylbenzene
C₁₀H₁₄, 134.222 g/mol.
1,1'-Carbonyldiimidazole
C₇H₆N₄O, 162.152 g/mol.
1,4-Benzodioxane-6-carboxylic Acid
used as a reactant
C₉H₈O₄, 180.159 g/mol.
1,8-Diazabicyclo(5.4.0)undec-7-ene
C₉H₁₆N₂, 152.241 g/mol.
Where these values came from
chemistry engine
What this page does not claim
Identifiers are copied from the source record, measured values are reported as published, and calculated values are marked as calculated. Nothing here is a hazard, purity or handling assessment — how the library is checked.
Where to next
More molecules under D
The rest of this shelf, a hundred names at a time.
Molar mass calculator
Work with C3H7NO in a calculation, with every element's contribution shown.
Molarity calculator
Grams of Dimethylformamide for a volume and a concentration, or the concentration a mass gives.
Open in ReactionLens
The full record in the workstation: every atom, every bond, and the reactions it appears in.